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Fat cell number increases through childhood and adolescence and generally stabilizes in adulthood.

The size of individual fat cells is remarkably variable, expanding and contracting with weight gain or weight loss. And as with most cell types in the body, adipocytes die eventually.

Michael Jensen, an endocrinologist and obesity researcher at the Mayo Clinic. Even among bariatric surgery patients, who can lose massive amounts of weight, the number of fat cells tends to remain the same, although the cells shrink in size, studies. People who are obese tend to have more fat cells than those who are not, and several studies have found an increase in Taking interviews4 proper fat adult womens cell number with weight regain following weight loss.

Kirsty L. Spalding, a cell biologist at the Karolinska Institute in Audlt and the lead author of a study showing that fat cells die and are replaced.

Beyond their role in storing Taking interviews4 proper fat adult womens, adipocytes secrete proteins and hormones that affect energy metabolism. Spalding said. One hypothesis is that those smaller cells might send signals to increase appetite and fat storage, which could help to explain why weight loss is so difficult to maintain, though much more research is needed. Do you have a health question?

Submit your question to Ask Well. See next articles. Q Once fat cells are formed, can you ever get rid of them?